Cai Lab News
New paper in Nature “Integrated spatial genomics reveals global architecture of single nuclei””
Take a look at the latest work from Cai Lab now in Nature. The work describes a new "single-cell multimodal imaging approach where genome organization, nuclear bodies, chromatin modifications and gene expression are determined in the same cell." -Nature Read it on...
Preprint: Global architecture of the nucleus in single cells by DNA seqFISH+ and multiplexed immunofluorescence
Check out our latest preprint with seqFISH-based integrated spatial genomics approach to study chromosome organization, transcriptional states, and chromatin states in single cells! biorxiv.org
Elsy Buitrago-Delgado: 100 Inspiring Hispanic/Latinx Scientists in America
Congratulations to Elsy Buitrago-Delgado for being named one of Cell's 100 Inspiring Hispanic/Latinx Scientists in America! Her research studying spatial organization inside cells in the first days of embryo development works to expand our understanding of mammalian...
New Publication: Detecting Proteins In Situ with DUET
Exciting new work by Cai Lab and lead author Yandong Zhang demonstrates a strategy for measuring proteins and their post-translational modification (PTM) states in single cells. From the paper: "Unlike nucleic acids, proteins cannot be amplified, making detection of...
Elsy Buitrago-Delgado: Awarded 2019 HHMI Hanna H. Gray Fellowship
Congratulations to Elsy for being one of fifteen scientists awarded the 2019 HHMI Hanna H. Gray Fellowship! Click here to learn more!
Congratulations to the new Dr. Yandong Zhang!
Congratulations Dr. Yandong Zhang for a successful PhD defense! His thesis work titled “Highly Multiplexed Imaging of E. Coli Chromosome and Sensitive Detection of Single-Cell Protein” details novel procedures for antibody-free protein barcoding and imaging in...
Lab Retreat 2019: Ojai, California
This May, the Cai Lab headed out to beautiful Ojai for a weekend of hiking, delicious food, and discussing our science! A fantastic time for all, can't wait till the next one!
New Super-Resolution Technique Published in Nature
Work at Cai lab published by first author Chee Huat (Linus) Eng in the March 25, 2019 issue of Nature. Also featured in Caltech News this week, the paper describes the novel RNA seqFISH+ technique for super-resolved imaging of the transcriptome in situ. Caltech News...