Nov 1, 2021 | Publications
Our latest work is now available in print inside the latest issue of Science. Using integrated spatial genomics technology, researchers at Cai Lab extensively investigated the single-cell nuclear architecture across cell types in the mouse brain cortex. Take a look...
Sep 10, 2021 | Publications
Exciting new work “Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis” is now out in Nature Biotechnology! This publication details a new method for studying cell fate decisions in complex tissues during development....
Jan 28, 2021 | Publications
Take a look at the latest work from Cai Lab now in Nature. The work describes a new “single-cell multimodal imaging approach where genome organization, nuclear bodies, chromatin modifications and gene expression are determined in the same cell.” -Nature...
Dec 1, 2020 | Announcements, Publications
Check out our latest preprint with seqFISH-based integrated spatial genomics approach to study chromosome organization, transcriptional states, and chromatin states in single cells! biorxiv.org
Aug 3, 2020 | Announcements, Publications
Exciting new work by Cai Lab and lead author Yandong Zhang demonstrates a strategy for measuring proteins and their post-translational modification (PTM) states in single cells. From the paper: “Unlike nucleic acids, proteins cannot be amplified, making...
Mar 28, 2019 | Announcements, In the News, Publications
Work at Cai lab published by first author Chee Huat (Linus) Eng in the March 25, 2019 issue of Nature. Also featured in Caltech News this week, the paper describes the novel RNA seqFISH+ technique for super-resolved imaging of the transcriptome in situ. Caltech News...
